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商品描述
| Product Name | Shepherdin (79 - 87)KHSSGCAFL |
| Size | 1 mg |
| Catalog # | AS-62748 |
| US$ | $73 |
| Purity | % Peak Area By HPLC ≥ 95% |
This is amino acids 79 to 87 fragment of shepherdin, a novel peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability. For its potent and broad antitumor activity, selectivity of action in tumor cells versus normal tissues, and inhibition of tumor growth in vivo without toxicity, shepherdin may offer a promising approach for rational cancer therapy. This sequence is also known as K79K90. | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Plescia, J. et al. Cancer Cell 7, 457 (2005). |
| Molecular Weight | 949.1 |
| KHSSGCAFL | |
| Sequence(Three-Letter Code) | H - Lys - His - Ser - Ser - Gly - Cys - Ala - Phe - Leu - OH |
| Product Citations | Fischer, CA. et al. (2014). A Bombesin-Shepherdin radioconjugate designed for combined extra-and intracellular targeting. Pharmaceuticals 7, 662. doi:10.3390/ph7060662. |
