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Abcam/Fura-2 AM, Ca2+ selective fluorescent indicator (ab120873)/1/ab120873

价格
面议
货号:ab120873
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品牌:Abcam
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商品描述

Overview

  • Product name

    Fura-2 AM, Ca2+ selective fluorescent indicator
  • Description

    High affinity Ca2+ selective fluorescent indicator
  • Alternative names

    • Fura 2 acetoxymethyl ester
  • Biological description

    High affinity Ca2+ selective fluorescent indicator (Kd = 145 nM). Rapidly metabolized by cytoplasmic esterases leading to the active dye Fura 2. Cell-permeable. Excitation spectrum dependent on [Ca2+]i. Ex340/380/Em505.

  • Purity

    >95%
  • General notes

    1 unit = 50μg

    • 1 mg - 1 x 1 mg vial
    • 20 units - 20 x 50 µg vials
    • 10 units - 10 x 50 µg vials
    • 50 µg - 1 x 50 µg vial

    Related protocols:

    Fura-2 AM imaging protocol

    Calcium imaging using Fura-2 AM in motor neurons

    Measurement of free cytosolic calcium concentration in single CHO-K1 cells

  • CAS Number

    108964-32-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-[6-[Bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]-2-benzofuranyl]-5-oxazolecarboxylic acid (acetyloxy)methyl ester
  • Molecular weight

    1001.86
  • Molecular formula

    C44H47N3O24
  • PubChem identifier

    3364574
  • Storage instructions

    Shipped at Room Temperature. Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=CC(=C(C=C1)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOC2=C(C=C3C(=C2)C=C(O3)C4=NC=C(O4)C(=O)OCOC(=O)C)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C
  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Chemical Type
    • Fluorescent tools
    • Biochemicals
    • Pharmacology
    • Signaling
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Research Area
    • Alzheimer"s Disease
    • Signaling
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Research Area
    • Diabetes
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Research Area
    • Diabetes
    • Signaling
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Research Area
    • Heart disease
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Research Area
    • Hypertension
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Research Area
    • Hypertension
    • Signaling
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Research Area
    • Obesity
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Research Area
    • Obesity
    • Signaling
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Research Area
    • Respiratory disease
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Research Area
    • Stroke
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Research Area
    • Stroke
    • Signaling
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Kits/ Lysates/ Other
    • Tools and Reagents
    • Fluorescent dyes and reagents
    • Biochemicals
    • Research Area
    • Cancer
    • Ca2+ signaling
    • Ionophores, Indicators & Chelators
    • Biochemicals
    • Chemical Type
    • Dyes, stains and fluorescent tools
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