| ProductName | Cat# | Clone# | Isotype | Applications | Reactivity | Unit/Size |
| AntiHumanPTX3 | PP-PPZ17115-00 | PPZ17115 | IgG2a | EL,WB,NW | Hu | 100ug/0.1ml |
*Description
Pentraxinsareasuperfamilyofconservedproteinscharacterizedbythepentraxindomain.CRPandSAParerecognizedasclassicalshortpentraxins,whereasPentraxin3(PTX3)belongstothelongpentraxins.CRPandSAPareinducedintheliverinresponsetoIL-6.Incontrast,PTX3isproducedbyavarietyoftissuesandcells,suchasvascularendothelialcells,macrophages,andneutrophils,predominantlyinresponsetoproinflammatorysignals(bacterialproducts,IL-1,andTNF).
SpecSheetPP-PPZ17115-00(PDFFile)
| Alias | PTX3,Pentraxin3 |
| GeNEBank | BC039733 |
| Nomenclature | |
| Origin | ProducedinBALB/cmouseascitesafterinoculationwithhybridomaofmousemyelomacells(NS-1)andspleencellsderivedfromamouseimmunizedwithrecombinanthumanPTX3(18-381aa).Epitope18-79a.a. |
| Specificity | ThisantibodyspecificallyrecognizeshumanPTX3.Notyettestedinotherspecies. |
| Purification | Ammoniumsulfatefractionation. |
| Formulation | Physiologicalsalinewith0.1%NaN3asapreservative. |
| Storage | Storeat2C-8Cuptoonemonth.Forlong-termstorage,thesolutionmaybefrozeninworkingaliquots.Repeatedfreezingandthawingisnotrecommended.Storageinafrost-freefreezerisnotrecommended. |
| Reference | |
| Note | Sodiumazidemayreactwithleadandcopperplumbingtoformexplosivemetalazides.FlushwithlargeamountsFormulationofwaterduringdisposal. |
Cautionmustbetakentoavoidcontactwithskinoreyes.Insuchacase,rinsethoroughlyatoncewithwater.Donotingest,inhale,orswallow.Seekmedicalattentionimmediately.Wearappropriateprotectiveclothingsuchaslaboratoryoveralls,safetyglassesandgloves.Itisstronglyadvisedthatthisproductshouldbehandledbypeoplewhohavebeenwelltrainedinlaboratorytechniquesandthatitishandledwithcarepursuanttotheprinciplesofgoodlaboratorypractice.Allchemicalsaredeemedpotentiallyharmful.Thevialispronetofallover.Usecaution,especiallywhenthelidisoff.
FORRESEARCHUSEONLY,NOTFORUSEINDIAGNOSTICPROCEDURES.
*Remark-Icon:
EL=ELISA,WB=WesternBlotting,NW=Non-reducingWesternBlotting,S=SuperShiftAssay.IP=Immunoprecipitation,IHC=Immunohistochemistory,CH=ChIPAssay
Hu=Human,Mo=Mouse,Ra=Rat
Manufacturedby:PerseusProteomics,Inc.
Questionsaboutthisproduct?Readytoplaceanorder? |
