The NucleoFast 96 PCR Clean-Up Kit and NucleoFast 96 PCR Plates use ultrafiltration for high recovery of nucleic acids in less than 20 minutes. The nucleic acids from PCR are collected on the filter membrane while the contaminants are filtered directly to the waste. The NucleoFast protocol is faster because it eliminates the intermediate wash steps required with silica-based purification systems. The 96 PCR Clean-Up Kit includes buffers and an elution plate. The sturdy, one-piece plate is easily adapted to automated processing. The purified PCR products are suitable for most common downstream applications, including capillary sequencing, microarray spotting, restriction analysis, labeling, or cloning.