Tested Species Reactivity:MouseProduct Format:LyophilizedApplication:CAAdditional Information:Description: GDF-5 is expressed in long bones during embryonic development and postnatally in articular cartilage. Mutations in the GDF-5 gene have been implicated in Hunter-Thompson type dwarfism and in Grebe Syndrome, which is characterized by short stature, extra digits, and short and deformed extremities.:::Bioactivity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 1.0-2.0 ug/ml.:::Endotoxin Level: Endotoxin level is <0.1 ng/ug="" of="" protein=""><1>Reconstitution and Storage:-20CPurity:98%Protein Sequence:APLANRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP LEYEAFHCEG LCEFPLRSHL EPTNHAVIQT LMNSMDPEST PPTCCVPTRL SPISILFIDS ANNVVYKQYE DMVVESCGCRSource:E. coliTarget Reference:Hatazawa Y, Ono Y, Hirose Y, Kanai S, Fujii NL, Machida S, Nishino I, Shimizu T, Okano M, Kamei Y, Ogawa Y. FASEB J. 2017 Nov 16. pii: fj.201700573R. doi: 10.1096/fj.201700573R. Diederichs S, Renz Y, Hagmann S, Lotz B, Seebach E, Richter W. J Biomed Mater Res B Appl Biomater. 2017 Oct 25. doi: 10.1002/jbm.b.34027.Datasheets/Manuals:Printable datasheet for OPTA01196Alias Symbols:Growth/Differentiation Factor-5, BMP-14, Cartilage-Derived Morphogenetic Protein-1 (CDMP-1)Molecular Weight:27.0 kDa 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
