Tested Species Reactivity:MousePredicted Species Reactivity:HumanProduct Format:LyophilizedApplication:CAAdditional Information:Description: CCL12 is a member of the CC family of chemokines and is a chemoattractant for eosinophils, monocytes and lymphocytes. CCL12 is expressed mainly in the lymph nodes and thymus and is involved in allergic reactions and normal immune responses. CCL12 exerts its effects through binding to to the CCR2 receptor.:::Bioactivity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-50.0 ng/ml.:::Endotoxin Level: Endotoxin level is <0.1 ng/ug="" of="" protein="">0.1><1>1>Reconstitution and Storage:-20CPurity:98%Protein Sequence:GPDAVSTPVT CCYNVVKQKI HVRKLKSYRR ITSSQCPREA VIFRTILDKE ICADPKEKWV KNSINHLDKT SQTFILEPSC LGSource:E. coliTarget Reference:Sarafi MN, Garcia-Zepeda EA, MacLean JA, Charo IF and Luster AD. 1997. J Exp. Med. 185: 99-109.
Kopydlowski KM, Salkowski CA, Cody MJ, van Rooijen N, Major J, Hamilton TA and Vogel SN. 1999. J Immunol. 163: 1537-1544.
Datasheets/Manuals:Printable datasheet for OPTA00801Alias Symbols:Monocyte Chemotactic Protein-5, CCL12Molecular Weight:9.3 kDa 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。