Tested Species Reactivity:Human, MousePredicted Species Reactivity:Mouse, RatProduct Format:Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA.Clonality:MonoclonalClone:Stat1Y701-3E6Isotype:Rabbit IgG1kHost:RabbitConjugation:SureLight 488Application:FCReconstitution and Storage:2-8CImmunogen:A synthetic phospho-peptide corresponding to residues surrounding Tyr701 of human phospho Stat1Purification:Protein A+GDatasheets/Manuals:Printable datasheet for OAAQ00135Target Post-Translational Modification:Phospho-Tyr701Application Info:For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application.Target Reference:Ramana CV, Gil MP, Schreiber RD, and Stark GR. (2002) Trends in Immunology. 23: 96-101.Avalle L, Pensa S, Regis G, Novelli F, and Poli V. (2012) JAK-STAT. 1: 65-72.Gene Symbol:STAT1Official Gene Full Name:signal transducer and activator of transcription 1Alias Symbols:CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91NCBI Gene Id:6772Protein Name:signal transducer and activator of transcription 1-alpha/betaDescription of Target:The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.Swissprot Id:P42224Protein Accession #:NP_009330.1Nucleotide Accession #:NM_007315.3Tissue Tool:Find tissues and cell lines supported by DNA array analysis to express STAT1. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express STAT1. 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
