Predicted Species Reactivity:Cow, Dog, Horse, Human, PigProduct Format:Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Clonality:PolyclonalHost:GoatReconstitution and Storage:Aliquot and store at -20C. Minimize freezing and thawing.Replacement Item:This antibody may replace item sc-18477 from Santa Cruz Biotechnology.Predicted Homology Based on Immunogen Sequence:Cow: 90%; Dog: 100%; Horse: 100%; Human: 100%; Pig: 100%Complete computational species homology data:ATXN2 Antibody (OAEB00310)Peptide Sequence:C-SEREGHSINTRDatasheets/Manuals:Printable datasheet for anti-ATXN2 antibody - OAEB00310Purity:Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.Application Info:Peptide ELISA: antibody detection limit dilution 1:2000.Western Blot: Preliminary experiments in Human Brain (Cerebellum and Cerebral Cortex) lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).Target Reference:* Dubois PC, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GA, Adány R, Aromaa A, Bardella MT, van den Berg LH, Bockett NA, de la Concha EG, Dema B, Fehrmann RS, Fernández-Arquero M, Fiatal S, Grandone E, Green PM, Groen HJ, Gwilliam R, Houwen RH, Hunt SE, Kaukinen K, Kelleher D, Korponay-Szabo I, Kurppa K, MacMathuna P, Maki M, Mazzilli MC, McCann OT, Mearin ML, Mein CA, Mirza MM, Mistry V, Mora B, Morley KI, Mulder CJ, Murray JA, N C, Oosterom E, Ophoff RA, Polanco I, Peltonen L, Platteel M, Rybak A, Salomaa V, Schweizer JJ, Sperandeo MP, Tack GJ, Turner G, Veldink JH, Verbeek WH, Weersma RK, Wolters VM, Urcelay E, Cukrowska B, Greco L, Neuhausen SL, McManus R, Barisani D, Deloukas P, Barrett JC, Saavalainen P, Wijmenga C, van Heel DA,; Multiple common variants for celiac disease influencing immune gene expression.; Nature genetics 2010 Apr 42 (4): 295-302.; Pubmed 20190752Gene Symbol:ATXN2Alias Symbols:ATXN2, ataxin 2, ATX2, FLJ46772, SCA2, TNRC13, trinucleotide repeat containing 13NCBI Gene Id:6311Protein Name:Ataxin-2Swissprot Id:Q99700Protein Accession #:NP_002964.3Tissue Tool:Find tissues and cell lines supported by DNA array analysis to express ATXN2. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express ATXN2. 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。