Tested Species Reactivity:HumanPredicted Species Reactivity:HumanProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Immunogen:The immunogen is a synthetic peptide directed towards the C terminal region of human HDAC3Purification:Affinity purifiedPeptide Sequence:Synthetic peptide located within the following region: VQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlBlocking Peptide:For anti-HDAC3 (ARP80651_P050) antibody is Catalog # AAP80651Datasheets/Manuals:Printable datasheet for anti-HDAC3 (ARP80651_P050) antibodyGene Symbol:HDAC3Official Gene Full Name:histone deacetylase 3Alias Symbols:HD3, RPD3, RPD3-2NCBI Gene Id:8841Protein Name:histone deacetylase 3Description of Target:Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.Swissprot Id:O15379Protein Accession #:NP_003874.2Nucleotide Accession #:NM_003883.3Protein Size (# AA):428Molecular Weight:49 kDaTissue Tool:Find tissues and cell lines supported by DNA array analysis to express HDAC3. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express HDAC3. 
我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
