Reconstitution and Storage:Centrifuge the vials after receiving and add 5 μl ddH2OTag:NoneDatasheets/Manuals:Printable datasheet for anti-RAF1 (ANA10389) antibodyGene Symbol:RAF1NCBI Gene Id:5894Description of Target:This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. Nucleotide Accession #:BC018119Tissue Tool:Find tissues and cell lines supported by DNA array analysis to express RAF1. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express RAF1. 
Protein Interactions:Prkab1; FYCO1; NPLOC4; TMEM70; COPS7A; DCAF8; PACSIN3; YWHAQ; RANBP9; RB1; PURA; MAP2K2; MAP2K1; MAPK3; MAPK1; PRKAR1A; MYBPC1; HSP90AA1; AKT1; FAM96B; MRAS; HUWE1; SHOC2; UBC; CDC37; IRS4; GPRASP2; STUB1; SH3KBP1; HIPK4; CDK20; YWHAB; TBXA2R; KRAS; YWHAE 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
