Tested Species Reactivity:HumanPredicted Species Reactivity:HumanProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Gene Symbol:BECN1Official Gene Full Name:beclin 1NCBI Gene Id:8678Protein Name:Beclin-1Swissprot Id:Q14457Protein Accession #:NP_001300927.1Nucleotide Accession #:NM_001313998.1Alias Symbols:ATG6, VPS30, beclin1Description of Target:This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.Protein Size (# AA):450Molecular Weight:52 kDaPurification:Affinity purifiedTissue Tool:Find tissues and cell lines supported by DNA array analysis to express BECN1. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express BECN1. Immunogen:The immunogen is a synthetic peptide directed towards the N terminal region of Human BECN1Peptide Sequence:Synthetic peptide located within the following region: TTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlBlocking Peptide:For anti-BECN1 (ARP86768_P050) antibody is Catalog # AAP86768Datasheets/Manuals:Printable datasheet for anti-BECN1 (ARP86768_P050) antibody 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。