Predicted Species Reactivity:Cow, Human, Mouse, RatProduct Format:Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.Clonality:PolyclonalHost:Rabbit Application:WBAdditional Information:Packaging : 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.Reconstitution and Storage:For long term storage -20C is recommended. Stable at -20C for at least 1 year.Gene Symbol:SYT1NCBI Gene Id:25716Protein Name:Synaptotagmin-1Swissprot Id:P21707Protein Accession #:NP_001028852.2Replacement Item:This antibody may replace item sc-12466 from Santa Cruz Biotechnology.Description of Target:Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release (Littleton and Bellen 1995). Recent studies indicate that synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane fusion (Zhang et al., 2002). It has recently been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size (Poskanzer et al., 2006).Molecular Weight:~65kDaPurification:Prepared from rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.Tissue Tool:Find tissues and cell lines supported by DNA array analysis to express SYT1. 
RNA Seq:Find tissues and cell lines supported by DNA array analysis to express SYT1. 
Immunogen:Synthetic peptide corresponding to amino acid residues within the synaptotagmin I protein.Predicted Homology Based on Immunogen Sequence:Cow; Human; Mouse; RatDatasheets/Manuals:Printable datasheet for OAPC00067Specificity:Specific for ~65k synaptotagmin I protein. 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
