Predicted Species Reactivity:Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, ZebrafishProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Gene Symbol:CCNA1Official Gene Full Name:cyclin A1NCBI Gene Id:8900Protein Name:Cyclin-A1Swissprot Id:P78396Protein Accession #:NP_003905Nucleotide Accession #:NM_001111045Description of Target:The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene.Protein Size (# AA):465Molecular Weight:52 kDaPurification:Affinity PurifiedTissue Tool:Find tissues and cell lines supported by DNA array analysis to express CCNA1. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express CCNA1. 
Immunogen:The immunogen is a synthetic peptide directed towards the following sequence AFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPPredicted Homology Based on Immunogen Sequence:Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 83%; Zebrafish: 83%Complete computational species homology data:Anti-CCNA1 (ARP30160_P050)Peptide Sequence:Synthetic peptide located within the following region: AFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlProtein Interactions:CKS2; CKS1B; HECW2; RHOBTB3; FZR1; PTMA; MYBL2; HIST1H1B; RB1; CTNNB1; CDKN1A; CDK2; CDK1; MCM6; MCM4; CDKN1B; COPS5; COPS6; CUL1; SKP2; PPP1CA; HIST1H1A; CDC20; CCNA1; RPA1; USP2; SRC; PGR; NPAT; UBC; SP1; CDT1; E2F1; INCA1; ARID2; CABLES1; KLHDC9; GPS2;Blocking Peptide:Available upon requestDatasheets/Manuals:Printable datasheet for anti-CCNA1 (ARP30160_P050) antibody 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
