Tested Species Reactivity:HumanPredicted Species Reactivity:Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, RatProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Gene Symbol:SIM2Official Gene Full Name:single-minded homolog 2 (Drosophila)NCBI Gene Id:6493Protein Name:Single-minded homolog 2Swissprot Id:Q14190Alias Symbols:SIM2, BHLHE15, Replacement Item:This antibody may replace item sc-8713 from Santa Cruz Biotechnology.Description of Target:This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.Protein Size (# AA):667Molecular Weight:73kDaPurification:Affinity purifiedTissue Tool:Find tissues and cell lines supported by DNA array analysis to express SIM2. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express SIM2. Immunogen:The immunogen is a synthetic peptide directed towards the middle region of Human SIM2Predicted Homology Based on Immunogen Sequence:Cow: 86%; Dog: 93%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 91%; Pig: 93%; Rabbit: 92%; Rat: 100%Complete computational species homology data:Anti-SIM2 (ARP33297_P050)Peptide Sequence:Synthetic peptide located within the following region: VLTEIEYKELQLSLEQVSTAKSQDSWRTALSTSQETRKLVKPKNTKMKTKConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlBlocking Peptide:For anti-SIM2 (ARP33297_P050) antibody is Catalog # AAP33297Datasheets/Manuals:Printable datasheet for anti-SIM2 (ARP33297_P050) antibody 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。