PredictedSpeciesReactivity:Mouse,RatProductFormat:Liquid.100ulin10mMHEPES(pH7.5),150mMNaCl,100ugpermlBSAand50%glycerol.Adequateamountofmaterialtoconduct10-miniWesternBlots.Clonality:PolyclonalHost:RabbitApplication:IHCAdditionalInformation:Packaging:100ulin10mMHEPES(pH7.5),150mMNaCl,100ugpermlBSAand50%glycerol.Adequateamountofmaterialtoconduct10-miniWesternBlots.ReconstitutionandStorage:Forlongtermstorage-20Cisrecommended.Stableat-20Cforatleast1year.GeneSymbol:SLC6A13NCBIGeneId:171163ProteinName:Sodium-andchloride-dependentGABAtransporter2SwissprotId:P31646ProteinAccession#:NP_598307.1DescriptionofTarget:Gamma-aminobutyricacid(GABA)istheprimaryinhibitoryneurotransmitterinthecentralnervoussystem,causingahyperpolarizationofthemembranethroughtheopeningofaCl-channelassociatedwiththeGABAAreceptor(GABAA-R)subtype.GABAplasmamembranetransporters(GATs)influencesynapticneurotransmissionbyhigh-affinityuptakeandreleaseofGABA.Todate,fourdistinctGABAtransportershavebeenidentified:GAT-1,GAT-2,GAT-3,andBGT-1.GAT-2isfoundinawiderangeofneuronalandnon-neuronalcellsincludingdendritesandaxonterminalsaswellasepithelialcellsandcellsformingthepiaandarachnoidcomplex(Contietal.,1999).MolecularWeight:~82kDaPurification:Preparedfromrabbitserumbyaffinitypurification.TissueTool:FindtissuesandcelllinessupportedbyDNAarrayanalysistoexpressSLC6A13. RNASeq:FindtissuesandcelllinessupportedbyDNAarrayanalysistoexpressSLC6A13. Immunogen:PeptidecorrespondingtoaminoacidresiduesfromtheC-terminalregionofratGAT-2.PredictedHomologyBasedonImmunogenSequence:Mouse;RatDatasheets/Manuals:PrintabledatasheetforOAPC00138Specificity:Specificforthe~82kGAT-2protein. 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。