Gene Symbol:ASLAlias Symbols:ASALNCBI Gene Id:435Protein Name:Argininosuccinate lyaseSwissprot Id:P04424Protein Accession #:NP_000039Nucleotide Accession #:NM_000048Description of Target:This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. Molecular Weight:40 Tissue Tool:Find tissues and cell lines supported by DNA array analysis to express ASL. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express ASL. 
我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
