Gene Symbol:TGFBR1Official Gene Full Name:transforming growth factor, beta receptor 1NCBI Gene Id:7046; 21812; Swissprot Id:P36897, Q64729, P80204Alias Symbols:TGFBR1, ALK5, SKR4, TGF-beta receptor type-1, TGFR-1, Activin A receptor type II-like protein kinase of 53kD, Activin receptor-like kinase 5, ALK-5, ALK5, Serine/threonine-protein kinase receptor R4, SKR4, TGF-beta type I receptor, TransforReplacement Item:This antibody may replace item sc-101574 from Santa Cruz Biotechnology.Description of Target:The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.Molecular Weight:56 kDaHost:RabbitClonality:PolyclonalPurification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Application:IF, ELISATissue Tool:Find tissues and cell lines supported by DNA array analysis to express TGFBR1. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express TGFBR1. Immunogen:Synthesized peptide derived from human TGFBeta RI around the phosphorylation site of S165. Location: 100-180aa.Predicted Species Reactivity:Human, Mouse, RatProduct Format:Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Reconstitution and Storage:Store at -20C. Avoid repeated freeze/thaw cycles.Concentration:1 mg/mlDatasheets/Manuals:Printable datasheet for anti-TGFBR1 (OASG07144) antibodyTarget Post-Translational Modification:Phospho-Ser165Specificity:Phospho-TGFBeta RI (S165) Polyclonal Antibody detects endogenous levels of TGFBeta RI protein only when phosphorylated at S165.Isotype:IgG 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。