NewEast/Active Rab3-GTP [26920][30 µL]/26920

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¥9900.00
货号:26920
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品牌:NewEastBio
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商品描述

CatalogNumber:  26920
GeneSymbol:  RAB3
Description:  Anti-ActiveRab3MouseMonoclonalAntibody
Background:  Rab3isamemberoftheRab-familyGTPasesandisspecificallytargetedtosynapticvesicles.
Immunogen:  RecombinantfulllengthproteinofactiveRab3A
Applications:  IP,IHC,IF
RecommendedDilutions:  1µgfor~2mgtotalcellularproteinsforIP1:100dilutionforIHC,IF
Concentration:  1mg/ml
Host:  mouse
Format:  Liquid
Clonality:  Monoclonal
Isotype:  IgG
Purity:  Purifiedfromascites
Storagebuffer:
Preservative:  no
Constituents:  PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol
SpeciesReactivity:  Anti-activeRab3antibodyrecognizesactiveRab3proteinsofvertebrates.
StorageConditions:  Storeat-20°C.Avoidfreeze/thawcycles
DownloadDatasheet:  
Immunoprecipitation/Westernblot:  
Rab3activationassay.Purifiedfull-lengthRab3AproteinswereimmunoprecipitatedaftertreatedwithGDP(lane1)orGTPγS(lane2).Immunoprecipitationwasdonewiththeanti-activeRab3monoclonalantibody(Cat.No.26920).Immunoblotwaswithananti-Rab3Apolyclonalantibody(Cat.No.21041).
 
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82601Rab3ActivationAssayKit 20assays $637   
26920ActiveRab3-GTPMonoclonalAntibody 30μL $495   
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Publications:
1.  VASPpromotesTGF-βactivationofhepaticstellatecellsbyregulatingRab11dependentplasmamembranetargetingofTGF-βreceptors    HepatologyVolume61,Issue1,pages361–374,January2015
2.  Rab5ActivityRegulatesGLUT4SortingintoInsulin-ResponsiveandNon-Insulin-ResponsiveEndosomalCompartments:APotentialMechanismforDevelopmentofInsulinResistance    Endocrinology.2014Sep;155(9):3315-28