品牌分类
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
| Catalog Number: 26922 |
| Gene Symbol: RAB35 |
| Description: Anti-Active Rab35 Mouse Monoclonal Antibody |
| Background: The Rab family of GTPases regulates eukaryotic vesicular membrane traffic. Rab35 is with both plasma membrane and endosomal localization, and has been implicated in diverse processes that include T-cell receptor recycling, oocyte yolk protein recycling and cytokinesis. Rab35 regulates neurite outgrowth in neuronal-like cells, and can induce protrusions. |
| Immunogen: Recombinant full length protein of active Rab35 |
| Applications: IP, IHC, IF |
| Recommended Dilutions: 1 µg for ~2 mg total cellular proteins for IP 1:100 dilution for IHC, IF |
| Concentration: 1 mg/ml |
| Host: mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti-active Rab35 antibody recognizes active Rab35 proteins of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
Download Datasheet:  |
| Immunoprecipitation/Western blot: |
| | Rab35 activation assay. Purified full-length Rab35 proteins were immunoprecipitated after treated with GDP (lane 1) orGTPγS (lane 2). Immunoprecipitation was done with the anti-active Rab35 monoclonal antibody (Cat. No. 26922). Immunoblot was with an anti-Rab35 polyclonal antibody (Cat. No. 21078). |
| Related Products | |||||
| Catalog# | Name | Size | Price | DataSheet | |
| 82801 | Rab35 Activation Assay Kit | 20 assays | $637 |  | |
| 26922 | Active Rab35-GTP Monoclonal Antibody | 30 μL | $495 | | |
| 21078 | Anti-Rab35 Rabbit Polyclonal Antibody | 100 μL | $219 | | |
| Publications: |
| 1. VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors HepatologyVolume 61, Issue 1, pages 361–374, January 2015 |
| 2. Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance Endocrinology. 2014 Sep;155(9):3315-28 |
