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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
CatalogNumber: 26919 |
GeneSymbol: RAB11 |
Description: Anti-ActiveRab11MouseMonoclonalAntibody |
Background: SmallGTPasesoftheRab-familyarecrucialelementsofthemachinerythatcontrolsmembranetraffic.Rab11hasbeenshowntocontroltrafficthroughtherecyclingendosome. |
Immunogen: RecombinantfulllengthproteinofactiveRab11 |
Applications: IP,IHC |
RecommendedDilutions: IP:1μgfor1~2mgtotalcellularproteinsIHC:1:50~100dilution |
Concentration: 1mg/ml |
Host: mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: IgG2b |
Purity: Purifiedfromascites |
Storagebuffer: |
Preservative: no |
Constituents: PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol |
SpeciesReactivity: Anti-activeRab11antibodyrecognizesactiveRab11fromvertebrates. |
StorageConditions: Storeat-20°C.Avoidfreeze/thawcycles |
DownloadDatasheet: |
Immunoprecipitation/Westernblot: |
Purifiedfull-lengthRab11proteinswereimmunoprecipitatedaftertreatedwithGDP(laneleft)orGTPγS(laneright).Immunoprecipitationwasdonewiththeanti-activeRab11monoclonalantibody(Cat.No.26919).Immunoblotwaswithananti-Rab5polyclonalantibody(Cat.No.21157). |
RelatedProducts | |||||
Catalog# | Name | Size | Price | DataSheet | |
26919 | ActiveRab11-GTPMonoclonalAntibody | 30μL | $495 | ||
83201 | Rab11ActivationAssayKit | 20assays | $637 | ||
26030 | Anti-Rab11MouseMonoclonalAntibody | 100μL | $239 |
Publications:1. VASPpromotesTGF-βactivationofhepaticstellatecellsbyregulatingRab11dependentplasmamembranetargetingofTGF-βreceptors HepatologyVolume61,Issue1,pages361–374,January2015 | 2. Rab5ActivityRegulatesGLUT4SortingintoInsulin-ResponsiveandNon-Insulin-ResponsiveEndosomalCompartments:APotentialMechanismforDevelopmentofInsulinResistance Endocrinology.2014Sep;155(9):3315-28 |
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