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苏州工业园区生物纳米园A4#216
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商品描述
| CatalogNumber: 26906 |
| GeneSymbol: Gnas |
| Description: Anti-ActiveGαs-GTPMouseMonoclonalAntibody |
| Background: HeterotrimericGproteinsarecriticalcellularsignaltransducers.Gαsrepresentsonesub-familyofGproteinsthatcouldmediatethestimulationofadenylylcyclases. |
| Immunogen: RecombinantfulllengthproteinofactiveGαs |
| Applications: IP,IHC |
| RecommendedDilutions: 1µgfor1~2mgtotalcellularproteinsforIP; 1:100dilutionforIHC |
| Concentration: 1mg/ml |
| Host: mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purifiedfromascites |
| Storagebuffer: |
| Preservative: no |
| Constituents: PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol |
| SpeciesReactivity: Anti-activeGαsantibodyrecognizesactiveGαsofvertebrates |
| StorageConditions: Storeat-20°C.Avoidfreeze/thawcycles |
DownloadDatasheet:  |
| Immunoprecipitation/Westernblot: |
| Gαsactivationassay.PurifiedGαsproteinswereloadedasacontrol(lanes1)orimmunoprecipitatedaftertreatedwithGDP(lane2)orGTPγS(lane3).Immunoprecipitationwasdonewiththeanti-activeGαsmonoclonalantibody(Cat.No.26906).Immunoblotwaswithananti-Gαsmonoclonalantibody(Cat.No.26006). |
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| Catalog# | Name | Size | Price | DataSheet | |
| sActivationAssayKit">80801 | GαsActivationAssayKit | 20assays | $637 |  | |
| s-GTP">26906 | ActiveGαs-GTPMonoclonalAntibody | 30μL | $495 | | |
| sMouseMonoclonalAntibody">26006 | Anti-GαsMouseMonoclonalAntibody | 100μL | $239 | | |
| sRabbitPolyclonalAntibody">21007 | Anti-GαsRabbitPolyclonalAntibody | 100μL | $219 | | |
Publications:| 1. GlucocorticoidactsonaputativeGprotein-coupledreceptortorapidlyregulatetheactivityofNMDAreceptorsinhippocampalneurons AmJPhysiolEndocrinolMetab.2012Apr1;302(7):E747-58 | 2. CRHactivationofdifferentsignalingpathwaysresultsindifferentialcalciumsignalinginhumanpregnantmyometriumbeforeandduringlabor JClinEndocrinolMetab.2012Oct;97(10):E1851-61 | 3. Estrogenicactiononarterialsmoothmuscle:permissiveformaintenanceofCRHR2expression Endocrinology.2012Apr;153(4):1915-24 | 4. Corticotropin-releasinghormonestimulatesmitotickinesin-likeprotein1expressionviaaPLC/PKC-dependentsignalingpathwayinhippocampalneurons MolCellEndocrinol.2012Oct15;362(1-2):157-64 | 5. Rapidactionsofxenoestrogensdisruptnormalestrogenicsignaling SteroidsVolume81,March2014,Pages36–42 | 6. NeuronalNF1/RASregulationofcyclicAMPrequiresatypicalPKCactivation Hum.Mol.Genet.(2014) | |
