NewEast/NFE2L2 Protein E79K mutant [10450][100ul]/10450

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¥6940.00
货号:10450
浏览量:107
品牌:NewEastBio
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商品描述

CatalogNumber:  10450
ProductName:  NFE2L2ProteinE79Kmutant
Synonyms:  Nuclearfactor(erythroid-derived2)-like2,Nrf2
Source:  Human,recombinantfulllength,His6-tag
ExpressionHost:  E.coli
MolecularWeight:  26kDa
Purity:  >99%bySDS-PAGE
Introduction:  NFE2L2proteinisencodedbyNFE2L2gene.Itisabasicleucinezipperproteinthatregulatestheexpressionofantioxidantproteinsthatprotectagainstoxidativedamagetriggeredbyinjuryandinflammation.SeveraldrugsthatstimulatetheNFE2L2pathwayarebeingstudiedfortreatmentofdiseasesthatarecausedbyoxidativestress.
AminoAcidSequence  (1-170)
MMDLELPPPGLPSQQDMDLIDILWRQDIDLGVSREVFDFSQRRKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQLDEKTGEFLPIQPAQHIQSETSGSANYSQVAHIPKSDALYFDDCMQLLAQTFPFVDDNEVSSATFQSLVPDIPGHIESPVFIATNQAQSPETSVA
Properties
PhysicalAppearance(form):  Dissolvedin20mMTris-HCl,pH8.0,150mMNaCl.
PhysicalAppearance(form):  Whiteorclear
Concentration:  1mg/mL
Storage:  -80°C
PreparationInstructions:  Addingof10mMβ-mercaptoethanolor1mMDTTintothesolutiontoprotecttheproteinisrecommendedandusingofnon-ionicdetergentssuchasn-Dodecylβ-D-maltoside(DoDM)orpolyethylenedetergents(e.g.C12E10)alsohelptostABIlizetheprotein.Avoidrepeatedfreezingandthawing.

ThepurityofHis-taggedNFE2L2E79KwasdeterminedbySDS-PAGEandCoomassieBrilliantBlueStaining.

References:  1.MoiPetal.,Proc.Natl.Acad.Sci.U.S.A.91(21):9926-30.2.GoldRetal.,N.Engl.J.Med.367(12):1098-107.
Datasheet:  
 
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