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商品描述
| Catalog Number: 26290 |
| Gene Symbol: ALK, CD246, NBLST3 |
| Description: Anti-ALK (D1225N) Mouse Monoclonal Antibody |
| Background: Anaplastic lymphoma kinase (ALK) also known as CD246 (cluster of differentiation 246) is a tyrosine kinase receptor that plays an important role in the development of the brain and nervous systems. Deficiencies in ALK, which most commonly as a fusion with other genes, are indicated in cancers. |
| Immunogen: A synthetic peptide from the internal region of ALK which includes the mutation of D1225N, human origin. |
| Applications: ELISA, WB |
| Recommended Dilutions: ELISA: 1:1000-1:5000WB: 1:500-1:2000 |
| Concentration: 1 mg/ml |
| Host: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes D1225N mutant, but not wild-type ALK of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
Download Datasheet:  |
| Western blot: |
| | Western blot analysis of recombinant ALK (D1225N) and wildtype proteins. Purified His-tagged ALK (D1225N) protein (1060-1620aa, 68KD, lane 2) and corresponding wildtype protein (lane 1) were blotted with anti-ALK (D1225N) monoclonal antibody (Cat. #26290). |
