品牌分类
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
| CatalogNumber: 26264 |
| GeneSymbol: MAP2K1;MAPKK1;MEK1;MKK1;PRKMK1 |
| Description: Anti-MEK1(I111S)MouseMonoclonalAntibody |
| Background: MEK1(alsoknownasextracellularsignal-regulatedkinases,ERKs)playsimportantroleintheMAPkinasecascade,whichtransducesmultipleextracellularsignalstocontrolcellgrowth,proliferationanddifferentiation.Activatedupongrowthfactorsstimulation,MEK1phosphorylatesMAPK3/ERK1andMAPK1/ERK2,thusactivatestheMAPpathwayandregulatestranscription.AbnormaloftheMEK1protein,includingpointmutations,areimplicatedindiseasessuchascardiofaciocutaneoussyndrome(CFC)andmelanoma. |
| Immunogen: AsyntheticpeptidefromtheinternalregionofMEK1whichincludesthemutationofI111S,humanorigin. |
| Applications: ELISA,WB,IHC |
| RecommendedDilutions: ELISA:1:1000-1:5000WB:1:500-1:1000IHC:1:50-1:100 |
| Concentration: 1mg/ml |
| Host: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: |
| Purity: Purifiedfromascites |
| Storagebuffer: |
| Preservative: no |
| Constituents: PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol |
| SpeciesReactivity: RecognizesI111Smutant,butnotwild-typeMEK1ofvertebrates. |
| StorageConditions: Storeat-20°C.Avoidfreeze/thawcycles |
DownloadDatasheet:  |
| Westernblot: |
| WesternblotanalysisofrecombinantMEK1(I111S)andwildtypeproteins.PurifiedHis-taggedMEK1(I111S)protein(lane2)andcorrespondingwildtypeprotein(lane1)wereblottedwithanti-MEK1(I111S)monoclonalantibody(Cat.#26264). |
| Immunofluorescence: |
 | ImmunofluorescenceofcellsexpressingMEK1proteinswithanti-MEK1(I111S)antibody.HEK293TcellsweretransfectedwithpCDNA3-GFP-MEK1(WT)plasmid(leftcolumn)orpCDNA3-GFP-MEK1(I111S)plasmid(rightcolumn),thenfixedandstainedwithanti-MEK1(I111S)monoclonalantibody(Cat.#26264). |
| RelatedProducts | |||||
| Catalog# | Name | Size | Price | DataSheet | |
| 26270 | Anti-MEK1(N382H)MouseMonoclonalAntibody | 100μL | $495 |  | |
| 26263 | Anti-MEK1(F53L)MouseMonoclonalAntibody | 100μL | $495 | | |
| 26266 | Anti-MEK1(P264S)MouseMonoclonalAntibody | 100μL | $495 | | |
| 26264 | Anti-MEK1(I111S)MouseMonoclonalAntibody | 100μL | $495 | | |
| 26222 | Anti-MEK1(Q56P)MouseMonoclonalAntibody | 100μL | $495 | | |
| 26224 | Anti-MEK1(D67N)MouseMonoclonalAntibody | 100μL | $495 | | |
