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苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
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0512-67156496
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商品描述
Description: | APPBP1/UBA3 is the heterodimeric E1 enzyme that conjugates Nedd8 to protein substrates.Nedd8 is conjugated onto the catalytic cysteine residue of UBA3 by formation of a thioester bond in an ATP-dependent reaction.The activated Nedd8 is then passed on to an E2 (Ubc12) to be finally attached to a substrate.Nedd8 is mainly conjugated on Cullins to increase the activity of the Cullin – RING E3 Ub ligases. |
Order #: | B1400-UBP |
Unit Size: | 25 µg |
Supplier: | UBPBio |
Restrictions: | Only available in selected countries. |
Shipping: | Dry ice |
Storage: | -80 °C |
Subcategory: | E1 Activating Enzymes |
More information: | Go to webpage |