- 抗体与细胞凋亡
- Proteins&&Protein controls
- Antibodies&&Vesicle Traffcking
- Antibodies&&G Protein Signalling
- 抗体、表观遗传学与核信号
- 抗体&标记抗体
- 抗体与心血管疾病
- Antibodies&&Organelle Markers
- Antibodies&&Other Antibodies
- Antibodies&&Structural proteins
- Antibodies&&Insect
- Antibodies&&Cell Biology
- 抗体&细菌、真菌、原生动物和病毒
- Antibodies&&CD Markers
- Antibodies&&Malaria
- 抗体和囊泡相关蛋白
- Antibodies&&Zebrafish
- 抗体与神经生物学
- Antibodies&&Other Controls
- 抗体和质膜
- 抗体和WB加载控制
ATXN3PolyclonalAntibody
CatalogNo.:AB0089-200
Price/Unit:EUR320.00
Source:Goat
Quantity/unitsize:600µg
Description:GoatpolyclonalantibodytoATXN3.Thisproteinappearstobeacomponentoftheubiquitinproteasomesystemandhasdeubiquitinaseactivity.Itmayalsohaverolesinneuroprotection,proteinhomeostasismaintenance,transcriptionalandCytoskeletonregulation,myogenesisanddegradationofmisfoldedchaperonesubstrates.TheproteincontainsQnrepeatsinthecodingregion,andtheexpansionoftheserepeatsfromthenormal13-36to68-79isonecauseofMachado-Josephdiseasealsoknownasspinocerebellarataxia-3,anautosomaldominantneurologicdisorder.Alternativenames:AT3,ATX3,ataxin-3,ataxin3varianth,autosomaldominantataxin3,ataxin3variantm,ataxin3variantref,JOS,josephin,Machado-Joseph,Machado-Josephdiseaseprotein1,MJD,MJD1,SCA3,spinocerebellarataxia3,olivopontocerebellarataxia3,spinocerebellarataxiatype3proteinantibody.
Form:Polyclonalantibodysuppliedasa200µl(3mg/ml)aliquotinPBS,20%glyceroland0.05%sodiumazide.Thisantibodyisepitope-affinitypurifiedfromgoatantiserum.
Immunogen:Purifiedrecombinantpeptidederivedfromwithinresidues120aato250aaofhumanATXN3producedinE.coli.
Specificity:DetectslevelsofATXN3proteinintransfectedcellswithGFP-ATXN3andendogenouslevelsinU118,SH-SY5Y,At-T20andhTERTcelllysatesbyWesternblot.
Reactivity:Reactsagainsthuman,rat,mouse,monkeyandcanineproteins.
Usage:Westernblot 1:250-1:2,000Immunofluorescence NDImmunohistochemistry(paraffin) NDImmunohistochemistry(frozen) ND
Reactivitychart
| Sample | WesternBlot | Immuno-fluorescence | Immuno-Histochemistry(p) | Immuno-Histochemistry(f) | human | +++ | ND | ND | ND | rat | +++ | ND | ND | ND | mouse | +++ | ND | ND | ND | canine | +++ | ND | ND | ND | monkey | +++ | ND | ND | ND |
|---|
Storage:Storeat-20Cforlongtermstorage.Storeat2-8Cforuptoonemonth.
Specialinstructions:Avoidfreeze/thawcycles.
References
Forresearchuseonly,notfordiagnosticuse
