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Creative PEGWorks /Methacrylate-PEG-Methacrylate, MW 10k/10g/PSB-3477-10g

价格
¥29000.00
货号:PSB-3477-10g
浏览量:50
品牌:Creative PEGWorks
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商品描述
Catalog No. :PSB-3477
Product Name :Methacrylate-PEG-Methacrylate,MW 10k
Description :

Methacrylate-PEG-Methacrylate is a linear bifunctional crosslinking PEG reagent with two Methacrylate( MAc ) groups that can be used for radical initiator induced polymerization or UV light sensitive photopolymerization. It is often used to form crosslinked polymer network and prepare PEG hydrogel.PEG-Methacrylate is an ester of PEG-OH with methacrylic acid. 4-Methoxyphenol or MeHQ at ~ 200 ppm is added as inhibitors.

References: 1. Thiol PEGylation of siRNA - Methods and Compositions for Improved Therapeutic Effects with siRNA, Patent US20080311040 A1, Text.

2. PEG Hydrogel- Bioartificial matrices for therapeutic vascularization, Proc Natl Acad Sci USA. 2010; 107(8): 3323–3328, Text.

3. PEG Hydrogel - Reductively Responsive siRNA-Conjugated Hydrogel Nanoparticles for Gene Silencing, J. Am. Chem. Soc., 2012, 134 (17), pp 7423–7430, Text.

4. Photocrosslinkable laminin-functionalized polyethylene glycol hydrogel for intervertebral disc regeneration, Acta Biomaterialia 10 (2014) 1102–1111,Text.

5. Hydrogel network design using multifunctional macromers to coordinate tissuematuration in ovarian follicle culture. Biomaterials 32.10 (2011): 2524-2531, Text

6. Multiplexed Dosing Assays by Digitally Definable Hydrogel Volumes. Adv. Healthcare Mater.,2016, 5: 244–254. doi:10.1002/adhm.201500542. Text

7. Microfluidic fabrication of bioactive microgels for rapid formation and enhanced differentiation of stem cell spheroids. Acta Biomater. 2016 Apr 1;34:125-132. Text

8.Microstructural alterations of sputum in cystic fibrosis lung disease, JCI Insight, 2016;1(18):e88198, Text.

Click here to view an expanded list of hundreds of publications citing Creative PEGWorks products.

Structure :
Price :
$300/1g
$950/5g
$1,450/10g
Quantity:
Quantity:
Quantity:
Creative PEGWorks提供可生物降解的聚酯,包括PLGA,PLA,PCL和PGA及其PEG共聚物。由于聚酯具有生物降解性和生物相容性,因此已在许多食品和药物管理局(FDA)批准的治疗设备中使用。这些聚合物在体内通过其酯键的水解而降解,以产生其原始单体,例如来自PLGA的乳酸和乙醇酸,这是各种代谢途径的两种副产物。PCL,聚己内酯通常用作长期可植入设备中的可植入生物材料。PLGA-聚(丙交酯-乙交酯共聚物)共聚物的分子量(MW)和单体(丙交酯与乙交酯)的摩尔比范围很广。典型的L对G进料比包括50:50、65:35、75:25和85:15。PLGA可以溶解在多种溶剂中-较高的丙交酯聚合物可以使用氯化溶剂溶解,而较高的乙交酯聚合物需要使用氟化溶剂,例如HFIP。PLA,聚乳酸或聚乳酸或聚丙交酯是可生物降解的脂肪族聚酯。由于单体中的手性中心(两种L-或D-对映体形式),因此存在几种PLA聚合物,例如异构纯的聚L-丙交酯(PLLA)和聚D-丙交酯(PDLA),以及外消旋混合物聚D,L-丙交酯(PDLLA)。PGA,聚乙交酯或聚乙醇酸具有异常的溶解性。PGA以其高分子量形式不溶于几乎所有常见的有机溶剂,但可溶于高度氟化的溶剂,例如六氟异丙醇(HFIP)和全氟丙酮,而低分子量PGA则更易溶于常见的有机溶剂。