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Creative PEGWorks /AC-PEG-AC, MW 1k/10g/PSB-343-10g

价格
¥26000.00
货号:PSB-343-10g
浏览量:127
品牌:Creative PEGWorks
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商品描述
Catalog No. :PSB-343
Product Name :AC-PEG-AC,MW 1k
Description :

Acrylate-PEG-Acrylate is a linear bifunctional crosslinking PEG reagent with two acrylate ( AC ) groups that can be used for radical initiator induced polymerization or UV light sensitive photopolymerization. It is often used to form crosslinked polymer network and preapre PEG hydrogel. Methacrylate-PEG-methacrylate is provided through our custom synthesis service. 4-Methoxyphenol or MeHQ at ~ 200 ppm is added as inhibitors.

References: 1. Thiol PEGylation of siRNA - Methods and Compositions for Improved Therapeutic Effects with siRNA, Patent US20080311040 A1, Text.

2. PEG Hydrogel- Bioartificial matrices for therapeutic vascularization, Proc Natl Acad Sci USA. 2010; 107(8): 3323–3328, Text.

3. PEG Hydrogel - Reductively Responsive siRNA-Conjugated Hydrogel Nanoparticles for Gene Silencing, J. Am. Chem. Soc., 2012, 134 (17), pp 7423–7430, Text.

4. Photocrosslinkable laminin-functionalized polyethylene glycol hydrogel for intervertebral disc regeneration, Acta Biomaterialia 10 (2014) 1102–1111, Text.

5. Hydrogel network design using multifunctional macromers to coordinate tissue maturation in ovarian follicle culture. Biomaterials 32.10 (2011): 2524-2531, Text

6. Multiplexed Dosing Assays by Digitally Definable Hydrogel Volumes. Adv. Healthcare Mater.,2016, 5: 244–254. doi:10.1002/adhm.201500542. Text

7. Microfluidic fabrication of bioactive microgels for rapid formation and enhanced differentiation of stem cell spheroids. Acta Biomater. 2016 Apr 1;34:125-132. Text

8. Microstructural alterations of sputum in cystic fibrosis lung disease, JCI Insight, 2016;1(18):e88198, Text.

9.Interfacial Coating Method for Amine-Rich Surfaces using Poly(ethylene glycol) Diacrylate Applied to Bioprosthetic Valve Tissue Models,ACS Appl. Bio Mater.2020,DOI:10.1021/acsabm.9b00911

Click here to view an expanded list of hundreds of publications citing Creative PEGWorks products.

Structure :
Price :
$250/1g
$850/5g
$1,300/10g
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Creative PEGWorks提供可生物降解的聚酯,包括PLGA,PLA,PCL和PGA及其PEG共聚物。由于聚酯具有生物降解性和生物相容性,因此已在许多食品和药物管理局(FDA)批准的治疗设备中使用。这些聚合物在体内通过其酯键的水解而降解,以产生其原始单体,例如来自PLGA的乳酸和乙醇酸,这是各种代谢途径的两种副产物。PCL,聚己内酯通常用作长期可植入设备中的可植入生物材料。PLGA-聚(丙交酯-乙交酯共聚物)共聚物的分子量(MW)和单体(丙交酯与乙交酯)的摩尔比范围很广。典型的L对G进料比包括50:50、65:35、75:25和85:15。PLGA可以溶解在多种溶剂中-较高的丙交酯聚合物可以使用氯化溶剂溶解,而较高的乙交酯聚合物需要使用氟化溶剂,例如HFIP。PLA,聚乳酸或聚乳酸或聚丙交酯是可生物降解的脂肪族聚酯。由于单体中的手性中心(两种L-或D-对映体形式),因此存在几种PLA聚合物,例如异构纯的聚L-丙交酯(PLLA)和聚D-丙交酯(PDLA),以及外消旋混合物聚D,L-丙交酯(PDLLA)。PGA,聚乙交酯或聚乙醇酸具有异常的溶解性。PGA以其高分子量形式不溶于几乎所有常见的有机溶剂,但可溶于高度氟化的溶剂,例如六氟异丙醇(HFIP)和全氟丙酮,而低分子量PGA则更易溶于常见的有机溶剂。