Dendro Amine-PEG-Dendro Amine or Hyperbranched Amine-PEG-Hyperbranched Amineconsists of a linear PEG10k core with two hyperbranched, dendritic wedges at both ends of the PEG chain. This series of products feature linear PEG functionalized with a bisMPA wedge with an average number of functional end groups (such as amine in the form of TFA salt). The hyperbranched structure is described as pseudo-generations of dendrimers G3, G4, G5 and G6 having 16, 32, 64, and 128 end functional groups, respectively. The MW for the entire molecule for G3, G4, G5 and G6 is 14,600, 19,400, 29,000 and 48,300 gram per mole. The MW of entire molecule is calculated from the MW of the linear PEG core combined with the number of dendritic structure and the functional groups. For amines, the MW includes the counter ions of trifluoroacetic acid salt. Products are fully characterized by HNMR CNMR and SEC (GPC). Full analytical data and ChemDraw structure of each generation are available upon request.

References:

1. High water content mouldable hydrogels by mixing clay and a dendritic molecular binder, Nature, 2010, 463, 339-343. Text.

2. Linear dendritic block copolymers as promising biomaterials for the manufacturing of soft tissue adhesive patches using visiblelight initiated thiol-ene coupling chemistry. Adv. Funct. Mater. 2015, 25, 6596-6605. Text.

3. Dendritic architectures based on bis-MPA: functional polymeric scaffolds for application-driven research, Chem. Soc. Rev. 2013, 42, 5858-5879. Text.

4. Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine PAMAM dendrimers, Biomaterials 2012, 33, 1970-1981. Text.

5. Multifunctional PEG: Synthesis, characterization and potential application of dendritic-linear-dendritic block copolymer hybrids. Macromolecules 2013, 46(10), 3726-3736. Text.

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