- 趋化因子
- Tau及其相关蛋白
- β淀粉样抗体
- Covid-19 Research Tools
- β-淀粉样肽,人,天然和突变,重组
- Covid-19/SARS-CoV-2相关;蛋白质
- 老年痴呆症产品
- Chemokine
- AD/PD相关蛋白
- Labeled Calmodulin Proteins
- 载脂蛋白/载脂蛋白
- AD/PD相关蛋白
- Apolipoprotein/Apo
- Tubulin
- β淀粉样肽,人,天然和突变,重组
- Beta-Amyloid Labeled Peptides, Synthetic
- Synuclein
- 神经退行性变相关化合物
- Alzheimer’s Products
- Beta Amyloid Peptides
- 抗体
Taupromotestheassemblyandmaintainsthestructureofmicrotubulesinneuronalcells3,4,5.Whilethefetalbraincontainsasingleisoformoftau(Tau-352)theadultbrainhasseveralisoforms.TauisbothphosphorylatedandO-GlcNAcylated6.Thenormalbraintaucontains2-3molesofphosphate/moleoftheprotein.InAlzheimerdiseasetauishyperphosphorylated,containing3-4-foldmorephosphate/moleoftheproteinthanthenormaltau7,8andisthemajorproteinsubunitofpairedhelicalfilaments(PHF)thatformtheneurofibrillarytangles(NFT).NFTaccumulationcorrelateswiththeclinicalprogressionofAlzheimer"sdisease.Tau4G11(TA-1001)isarPeptideexclusiveTauMonoclonalAntibodythatbinds4outofthe6Tauisoforms.ItspecificallybindsTau-381,Tau-410,Tau-412,andTau-441whichallcontainatleastoneaminoterminalinsert.


