These preformed fibrils of α-synuclein may be used as a model for the pathogenic form of α-synuclein in numerous neuropathies. Sourced from E. coli, α-synuclein fibrils were prepared and confirmed by thioflavin assay and electron microscopy. The fibrils can be used for either in vitro requirements such as fibril stability, drug design, aggregation studies, or treatment models. Applications for in vivo experiments include in vivo seeding experiments and preformed fibril injections. The use of these preformed fibrils for in vivo can be advantageous, due to the level of α-synuclein fibrils being more physiological than viral-based or transgenic methods. Alpha-synuclein preformed fibrils may also be used in the study of Parkinson’s Disease or Lewy Body Dementia.

用产品只提供给进一步的科研使用，不可应用于治疗等其他方面。 rPeptide是设在雅典，美国佐治亚州的一家生物技术公司，是一种在阿尔茨海默氏症和帕金森氏病的研究提供研究产品（重组多肽和蛋白质，抗体，试剂）市场的*。rPeptide还提供定制服务的范围从分子生物学，蛋白表达和纯化，13C和15N的多肽和蛋白质的统一标识。 rPeptide有一个专有的平台载体技术，使可溶性肽/蛋白在大肠杆菌中（如淀，β-淀粉样蛋白，瘦素，亲胰岛素）历史上的困难肽/蛋白表达。 商品名称    商品货号    商品品牌 Beta-Amyloid (1-40), Mouse, Rat    A-1007-1    rPeptide Beta-Amyloid (1-40), Starter Kit    A-1150-1    rPeptide Beta-Amyloid (1-40), Starter Kit    A-1150-2    rPeptide Beta-Amyloid (1-40), Ultra Pure, HCl    A-1156-1    rPeptide Beta-Amyloid (1-40), Ultra Pure, HCl    A-1156-2    rPeptide Beta-Amyloid (1-40), Ultra Pure, HFIP    A-1153-1    rPeptide Beta-Amyloid (1-40), Ultra Pure, HFIP    A-1153-2    rPeptide Beta-Amyloid (1-40), Ultra Pure, NaOH    A-1155-1    rPeptide Beta-Amyloid (1-40), Ultra Pure, NaOH    A-1155-2    rPeptide Beta-Amyloid (1-40), Ultra Pure, TFA    A-1001-1    rPeptide Beta-Amyloid (1-40), Ultra Pure, TFA    A-1001-2    rPeptide Beta-Amyloid (1-40, D23N)    A-1013-1    rPeptide Beta-Amyloid (1-40, D23N)    A-1013-2    rPeptide Beta-Amyloid (1-40, F4W)    A-1011-1    rPeptide Beta-Amyloid (1-40, F4W)    A-1011-2    rPeptide