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FORMAzol®ismolecularBIOLOGygradeformamidethatremainsstableforoneyearwhenstoredat4Corfortwoyearswhenstoredat-20C.ThisstABIlizedformamideservesasanexcellentRNAsolubilizerandhasbeenshowntohaveseveraladvantagesoverwaterasanRNAsolubilizationagent(1).RNAsolubilizedinFORMAzolisprotectedfromdegradationbyRNaseandcanbestoredat-20Cinsteadof-70C.SolubilizationofRNAinformamidefacilitatestheapplicationofRNAtoaformaldehyde-agarosegelinnorthernanalysis.
References
- Chomczynski,P.SolubilizationinformamideprotectsRNAfromdegradation.NucleicAcidsRes.20(14):3791-3792.1992.
