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蚂蚁淘在线 / 品牌中心 / BioXcell / BioXcell/InVivoMAb recombinant CTLA-4-Ig (hum/hum)/REGULAR: 5MG/BE0099-R005mg
商品描述
AboutInVivoMAbanti-mouse4-1BB(CD137)
The17B5monoclonalantibodyreactswithmouse4-1BB,aTNFreceptorsuperfamilymemberalsoknownasCD137.4-1BBisa39kDatransmembraneproteinexpressedbyTlymphocytes,NKcells,dendriticcells,granulocytes,andmastcells.Uponbindingitsligand4-1BBL,4-1BBprovidescostimulatorysignalstobothCD4andCD8TcellsthroughtheactivationofNF-κB,c-Junandp38downstreampathways.Theimportanceofthe4-1BBpathwayhasbeenunderscoredinseveraldiseases,includingcancer.The17B5antibodyhasbeenshowntoblock4-1BB-mediatedTcellproliferationinvitro.
InVivoMAbanti-mouse4-1BB(CD137)Specifications
| Isotype | SyrianHamsterIgG |
| RecommendedIsotypeControl(s) | InVivoMAbpolyclonalSyrianhamsterIgG(BE0087) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | Notavailableorunknown |
| ReportedApplications |
|
| Endotoxin |
|
| Purity |
|
| Formulation |
|
| Sterility | 0.2µmfiltration |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinA |
| Storage | Theantibodysolutionshouldbestoredatthestockconcentrationat4°C.Donotfreeze. |
| RRID | AB_2687819 |
| MolecularWeight | 150kDa |
