AboutInVivoMAbanti-human/monkeyCD40L(CD154)
The5C8monoclonalantibodyreactswithhumanandcynomolgusmonkeyCD154alsoknownasCD40ligand.CD154existsasa39kDaaccessorymoleculeandbelongstotheTNFsuperfamilyofcytokines.CD154isprimarilyexpressedonthesurfaceofactivatedCD4+Tlymphocytesbutcanalsobeexpressedbyplatelets,mastcells,macrophages,basophils,NKcells,Blymphocytes,CD8+Tlymphocytesaswellasnon-hematopoieticcellsincludingsmoothmusclecells,endothelialcells,andepithelialcells.CD154signalsthroughCD40andisthoughttoplayakeyroleinTandBlymphocyteco-stimulation.The5C8monoclonalantibodyhasbeenreportedtoblockCD40L-CD40interactions.
InVivoMAbanti-human/monkeyCD40L(CD154)Specifications
Isotype | MouseIgG2a |
RecommendedIsotypeControl(s) | InVivoMAbmouseIgG2aisotypecontrol,unknownspecificity(BE0085) |
RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
Immunogen | HumanD1.1Tcellline |
ReportedApplications |
|
Endotoxin |
|
Purity |
|
Formulation | PBS,pH7.0 |
Sterility | 0.2μmfiltration |
Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
Purification | ProteinG |
Storage | Theantibodysolutionshouldbestoredatthestockconcentrationat4°C.Donotfreeze. |
RRID | AB_2687815 |
MolecularWeight | 150kDa |