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BioXcell/InVivoMAb recombinant CTLA-4-Ig (hum/hum)/DISCOUNTED ACADEMIC OR NON PROFIT: 100MG/BE0099-A100mg

价格
¥1900.00
货号:BE0099-A100mg
浏览量:127
品牌:BioXcell
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商品描述

AboutInVivoMAbanti-human/monkeyCD40L(CD154)

The5C8monoclonalantibodyreactswithhumanandcynomolgusmonkeyCD154alsoknownasCD40ligand.CD154existsasa39kDaaccessorymoleculeandbelongstotheTNFsuperfamilyofcytokines.CD154isprimarilyexpressedonthesurfaceofactivatedCD4+Tlymphocytesbutcanalsobeexpressedbyplatelets,mastcells,macrophages,basophils,NKcells,Blymphocytes,CD8+Tlymphocytesaswellasnon-hematopoieticcellsincludingsmoothmusclecells,endothelialcells,andepithelialcells.CD154signalsthroughCD40andisthoughttoplayakeyroleinTandBlymphocyteco-stimulation.The5C8monoclonalantibodyhasbeenreportedtoblockCD40L-CD40interactions.

InVivoMAbanti-human/monkeyCD40L(CD154)Specifications

Isotype

MouseIgG2a

RecommendedIsotypeControl(s)InVivoMAbmouseIgG2aisotypecontrol,unknownspecificity(BE0085)
RecommendedInVivoPureDilutionBufferInVivoPurepH7.0DilutionBuffer(IP0070)
Immunogen

HumanD1.1Tcellline

ReportedApplications
  • invitroblockingofCD40/CD40Lsignaling
  • invivoblockingofCD40/CD40Lsignaling
  • Immunoprecipitation
  • Flowcytometry
Endotoxin
  • <2EU/mg(<0.002EU/μg)
  • DeterminedbyLALgelclottingassay
Purity
  • >95%
  • DeterminedbySDS-PAGE
Formulation

PBS,pH7.0

Sterility

0.2μmfiltration

Production

Purifiedfromtissueculturesupernatantinananimalfreefacility

Purification

ProteinG

Storage

Theantibodysolutionshouldbestoredatthestockconcentrationat4°C.Donotfreeze.

RRID

AB_2687815

MolecularWeight

150kDa

二、融合蛋白产品系列:Bio X Cell公司的重组蛋白是通过DNA技术生产,具有高纯度(SDS-PAGE测定达到95%以上)和低内毒素特性(LAL凝胶凝结试验小于2 EU /毫克),不含防腐剂或稳定剂,适用于生命科学研究及体内临床前治疗研究。在该系列产品总共包括5款优质融合蛋白,InVivoMAb重组CTLA-4-lg,InVivoMAb重组FLT-3L--lg,InVivoMAb重组小鼠Angiostatin-lg以及InVivoMAb重组小鼠Endostatin-lg。