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BioX cell/InVivoPlus anti-mouse NK1.1/BP0036/5MG

价格
¥12900.00
货号:BP0036
浏览量:91
品牌:BioXcell
服务
全国联保
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商品描述

ThePK136monoclonalantibodyreactswithmouseNK1.1alsoknownasCD161b/CD161c,KLRB1,NKR-P1AandLy-55.NK1.1isatypeIIintegralmembraneglycoproteinwithaC-typelectindomainandisencodedbytheKlrb1c/NKR-P1Cgene.NK1.1playsrolesinNKcellactivationanddifferentiation,IFN-γproduction,cytotoxicgranulerelease,andisthoughttobeinvolvedinthegenerationofTh2cells.NK1.1ispredominantlyexpressedasadisulfide-linkedhomodimeronNKcellshowever,itisalsoexpressedonNK-Tcells,ararepopulationofTlymphocytes.NK1.1isonlyexpressedbyC57BL/6,FVB/N,andNZBstrainsofmiceandnotAKR,BALB/c,CBA/J,C3H,DBA/1,DBA/2,NOD,SJL,and129strains.

Isotype

MouseIgG2a, κ

RecomendedIsotypeControl(s)InVivoPlusmouseIgG2aisotypecontrol,unknownspecificity
RecommendedInVivoPureDilutionBufferInVivoPurepH7.0DilutionBuffer
Immunogen

MousespleenandbonemarrowcellsenrichedforNK1+cells

ReportedApplications
  • invivoNKcelldepletion
  • Flowcytometry
Endotoxin
  • <1EU/mg(<0.001EU/μg)
  • DeterminedbyLALgelclottingassay
Purity
  • >95%
  • DeterminedbySDS-PAGE
Aggregation
  • <5%
  • DeterminedbyDS
Formulation
  • PBS,pH7.0
  • ContainsnostABIlizersorpreservatives
Sterility

0.2μMfiltered

Production

Purifiedfromtissueculturesupernatantinananimalfreefacility

Purification

ProteinA

Storage

Undilutedat4°Cinthedark

MurinePathogenTestResults
  • MouseNorovirus:Negative
  • MouseParvovirus:Negative
  • MouseMinuteVirus:Negative
  • MouseHepatitisVirus:Negative
  • ReovirusScreen:Negative
  • LymphocyticChoriomeningitisvirus:Negative
  • LactateDehydrogenase-ElevatingVirus:Negative
  • MouseRotavirus:Negative
  • TheilerÕsMurineEncephalomyelitis:Negative
  • Ectromelia/MousepoxVirus:Negative
  • Hantavirus:Negative
  • PolyomaVirus:Negative
  • MouseAdenovirus:Negative
  • SendaiVirus:Negative
  • MycoplasmaPulmonis:Negative
  • PneumoniaVirusofMice:Negative
  • MouseCytomegalovirus:Negative
  • KVirus:Negative
References
SDSSheet
二、融合蛋白产品系列:Bio X Cell公司的重组蛋白是通过DNA技术生产,具有高纯度(SDS-PAGE测定达到95%以上)和低内毒素特性(LAL凝胶凝结试验小于2 EU /毫克),不含防腐剂或稳定剂,适用于生命科学研究及体内临床前治疗研究。在该系列产品总共包括5款优质融合蛋白,InVivoMAb重组CTLA-4-lg,InVivoMAb重组FLT-3L--lg,InVivoMAb重组小鼠Angiostatin-lg以及InVivoMAb重组小鼠Endostatin-lg。