品牌分类
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
TheR2-9A5monoclonalantibodyreactswithmouseinterleukin-12(IL-12),aheterodimeric75kDa(p75)cytokineconsistingoftwocovalentlylinkedsubunits,40kDa(p40)and35kDa(p35).IL-12issecretedbyactivatedmonocytes,macrophages,dendriticcellsandTcellsinresponsetobacterialpathogensorproductssuchaslipopolysaccharides(LPS).IL-12isapotentregulatorofcell-mediatedimmuneresponsesandplaysakeyroleinthedevelopmentofTh1responses,leADIngtoIFNγandIL-2production.TheR2-9A5antibodyhasbeenshowntoneutralizetheBIOLOGicaleffectsofIL-12whenadmiNISTeredinvivo.
| Isotype | RatIgG2b |
| RecomendedIsotypeControl(s) | InVivoMAbratIgG2bisotypecontrol,anti-keyholelimpethemocyanin |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH8.0DilutionBuffer |
| Immunogen | RecombinantmouseIL-12p75 |
| ReportedApplications |
|
| Endotoxin |
|
| Purity |
|
| Formulation |
|
| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Undilutedat4°Cinthedark |
References
SDSSheet
