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Monitor NF-κB signaling in Jurkat cells
Speed your studies with this pre-built Jurkat cell line for monitoring NF-κB signaling in real time. We’ve already integrated an expression cassette that includes NF-κB-responsive transcriptional elements upstream of a minimal CMV promoter (mCMV)-GFP cassette. Expression of GFP (up to 30-fold over background) only occurs in the presence of active NF-κB signaling, enabling screening for genetic and/or small molecule inhibitors and activators of the NF-κB signaling pathway.
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