BRAFBreakApartFISHProbe
BRAFmutationshavebeenassociatedwithvariouscancersincluding:non-Hodgkinlymphoma,colorectalcancer,malignantmelanoma,papillarythyroidcarcinoma,non-smallcelllungcarcinoma,andadenocarcinomaofthelung.TheBRAFgeneencodesaserine/threoninekinasebelongingtotheRAS/RAF/MEK/ERK/MAPKpathway.Thisproteinplaysaroleinregulatingcelldivision,differentiation,andsecretion.
EmpireGenomicshasdevelopedaBRAFBreakApartFISHProbewhichcanbeusedtodetectarearrangementoftheBRAFgene.Theprobescomelabeledinorangeandgreen,andyoumayalsochoosetocustomizetheprobetomeetyourneeds.
*USA–ASR,EU–CEMarked(Orange-Greencoloroptiononly)
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