BRAFFISHProbe
EmpireGenomicshasdevelopedaBRAFFISHProbeassaywhichcanbeusedtodetectBRAFgeneaneusomy.Theprobecomeslabeledinorange,andyoumayalsochoosetocustomizetheprobetomeetyourneeds.TheBRAFgeneencodesaserine/threoninekinasebelongingtotheRAS/RAF/MEK/ERK/MAPKpathway.Thisproteinplaysaroleinregulatingcelldivision,differentiation,andsecretion.Mutationsinthisgenehavebeenassociatedwithvariouscancersincluding:non-Hodgkinlymphoma,colorectalcancer,malignantmelanoma,papillarythyroidcarcinoma,non-smallcelllungcarcinoma,andadenocarcinomaofthelung.
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