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商品描述
| Description | BAY-885 is a highly potent and selective ERK5 inhibitor. | |
|---|---|---|
| Targets |
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| In vitro | BAY-885 shows potent ERK5 kinase and transcriptional inhibition in the SN12C-MEF2 reporter cell line (IC50 = 115 nM/IC90 = 691 nM) and has no effects on a reporter control cell line with constitutive luciferase expression (SN12C-CMV-luc, IC50 > 30 μM), thereby ruling out potential effects as a general inhibitor of transcription or translation.[1] |
