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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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商品描述
| Description | BAY 2402234 is a novel and selective dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 1.2 nM. | ||
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| Targets |
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| In vitro | BAY 2402234 induces differentiation and inhibits proliferation in AML cell lines across multiple AML subtypes.[1] | ||
| In vivo | BAY 2402234 shows strong monotherapy efficacy and induces differentiation in AML xenograft models in vivo.[1] |
