品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Specifications
| SPECIES REACTIVITY: | Human |
|---|---|
| TESTED APPLICATIONS: | WB |
| APPLICATIONS: | For WB starting dilution is: 1:1000 |
| USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
| PREDICTED MOLECULAR WEIGHT: | 47 kDa |
| IMMUNOGEN: | This AADAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human AADAT. |
| HOST SPECIES: | Rabbit |
Properties
| PURIFICATION: | This antibody is purified through a protein A column, followed by peptide affinity purification. |
|---|---|
| PHYSICAL STATE: | Liquid |
| BUFFER: | Supplied in PBS with 0.09% (W/V) sodium azide. |
| CONCENTRATION: | 0.5 mg/ml |
| STORAGE CONDITIONS: | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| CLONALITY: | Polyclonal |
| ISOTYPE: | Rabbit Ig |
| CONJUGATE: | Unconjugated |
Additional Info
| ALTERNATE NAMES: | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial, KAT/AadAT, 2-aminoadipate aminotransferase, 2-aminoadipate transaminase, Alpha-aminoadipate aminotransferase, AadAT, Kynurenine aminotransferase II, Kynurenine--oxoglutarate aminotransferase II, Kynurenine--oxoglutarate transaminase 2, Kynurenine--oxoglutarate transaminase II, AADAT, KAT2 |
|---|---|
| ACCESSION NO.: | Q8N5Z0 |
| PROTEIN GI NO.: | 46395904 |
| OFFICIAL SYMBOL: | AADAT |
| GENE ID: | 51166 |
Background
| BACKGROUND: | This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist. |
|---|---|
| REFERENCES: | 1) Han, Q., et al. Biosci. Rep. 28(4):205-215(2008) | 2) Rossi, F., et al. J. Biol. Chem. 283(6):3559-3566(2008) | 3) Han, Q., et al. J. Biol. Chem. 283(6):3567-3573(2008) | 4) Lamesch, P., et al. Genomics 89(3):307-315(2007) |
