Primary Human Dermal Lymphatic Endothelial Cells (HDLEC) are a subpopulation of the Human Dermal Endothelial Cells. They are isolated from the dermis of juvenile foreskin and adult skin (different locations) from a single donor.(Human Dermal Blood Endothelial Cells (HDBEC) from the same donor are available on request.)

The cells are routinely analyzed by flow cytometric analysis and immunofluorescent staining:> 95% of the cells are CD31 positive and podoplanin positive.

Lymphatic vessels transport excess fluids from tissues to the circulatory system and are a major component of the immune system. The transported fluid is nearly cell free. The vessels are highly permeable, because they lack a continuous basal membrane. Lymphatic endothelial cells are involved in pathological alterations of the lymphatic system. During tumor lymphangiogenesis, the lymphatic endothelial cells build new vessels that infiltrate tumors, attract tumor cells, and induce tumor cell metastasis.

NEW: Our HDLEC are now also available from HLA-typed donors.

Available formats:

• Cryopreserved: Cryogenic vial containing 500.000 viable cells.
• Proliferating: >500.000 viable cells shipped in growth medium (T25 flask).
• Cell pellet: 1 million cells dissolved in 200µl RNAlater© for subsequent RNA, DNA or protein analysis. Cell pellets cannot be revived.

PromoKine细胞生物学(Cell Biology)是在显微、亚显微和分子水平三个层次上，研究细胞的结构、功能和各种生命规律的一门科学。细胞生物学由细胞学发展而来，细胞学是关于细胞结构与功能(特别是染色体)的研究。现代细胞生物学从显微水平、超微水平和分子水平等不同层次研究细胞的结构、功能及生命活动。在我国基础学科发展规划中，细胞生物学与分子生物学、神经生物学和生态学并列为生命科学的四大基础学科。