Primary Human Dermal Blood Endothelial Cells (HDBEC) are a subpopulation of the Human Dermal Endothelial Cells. They are isolated from the dermis of juvenile foreskin and adult skin (different locations) from a single donor.(Human Dermal Lymphatic Endothelial Cells (HDLEC) from the same donor are available on request.)

The cells are routinely analyzed by flow cytometric analysis and immunofluorescent staining: they are > 95% CD31 positive and stain positive for von Willebrand factor. In addition, they are > 90% negative for podoplanin and stain negative for smooth muscle specific alpha-actin.

Blood Endothelial Cells have a key function in physiological processes like vessel tonus, capillary permeability, blood coagulation, fibrolysis, and angiogenesis. They are also useful for disease studies of atherosclerosis, tumor genesis, and thrombosis.

NEW: Our HDBEC are now also available from HLA-typed donors.

Available formats:

• Cryopreserved: Cryogenic vial containing 500.000 viable cells.
• Proliferating: >500.000 viable cells shipped in growth medium (T25 flask).
• Cell pellet: 1 million cells dissolved in 200µl RNAlater© for subsequent RNA, DNA or protein analysis. Cell pellets cannot be revived.

PromoKine细胞生物学(Cell Biology)是在显微、亚显微和分子水平三个层次上，研究细胞的结构、功能和各种生命规律的一门科学。细胞生物学由细胞学发展而来，细胞学是关于细胞结构与功能(特别是染色体)的研究。现代细胞生物学从显微水平、超微水平和分子水平等不同层次研究细胞的结构、功能及生命活动。在我国基础学科发展规划中，细胞生物学与分子生物学、神经生物学和生态学并列为生命科学的四大基础学科。