Primary Human Cardiac Microvascular Endothelial Cells (HCMEC) are isolated from heart ventricles from a single donor. The cells are routinely analyzed by immunofluorescent staining: they stain positive for CD31 and Willebrand factor and negative for smooth muscle alpha-actin.

HCMEC intensively interact with cardiomyocytes and therefore have a characteristic phenotype different from other microvascular endothelial cells. HCMEC play an important role in the physiological regulation of coronary blood flow and capillary exchange. Medical conditions such as hypertrophy, ischemia, hypertension, and diabetes mellitus are associated with endothelial dysfunction.

NEW: Our HCMEC are now also available from HLA-typed donors.

Available formats:

• Cryopreserved: Cryogenic vial containing 500.000 viable cells.
• Proliferating: >500.000 viable cells shipped in growth medium (T25 flask).
• Cell pellet: 1 million cells dissolved in 200µl RNAlater© for subsequent RNA, DNA or protein analysis. Cell pellets cannot be revived.

PromoKine细胞生物学(Cell Biology)是在显微、亚显微和分子水平三个层次上，研究细胞的结构、功能和各种生命规律的一门科学。细胞生物学由细胞学发展而来，细胞学是关于细胞结构与功能(特别是染色体)的研究。现代细胞生物学从显微水平、超微水平和分子水平等不同层次研究细胞的结构、功能及生命活动。在我国基础学科发展规划中，细胞生物学与分子生物学、神经生物学和生态学并列为生命科学的四大基础学科。