Monocytes (Mo) are immature phagocytic cells circulating in the blood. Acting as antigen-presenting immune cells, they can phagocytize and degrade microbes and particulate matter. Monocytes can differentiate into several different cell types. The most common applications for Monocytes are the in vitro differentiation into monocyte-derived dendritic cells (moDC), macrophages, and osteoclasts as well as their use as phagocytic immune cells in immunology and infection biology.

CD14 belongs to the family of LPS receptor antigens and is strongly expressed on the majority of Monocytes. Thus, binding of immunomagnetic particles to this antigen is employed for purification of PromoCell CD14 -Monocytes (hMoCD14 -PB) from Mononuclear Cells (MNC).

PromoCell Human CD14 Monocytes are isolated from fresh peripheral blood. After isolation of the ultra-pure mononuclear cell fraction by proprietary methods, the CD14 Monocytes are isolated by positive selection with > 95% purity.

NEW: Our hMoCD14+ -PB are now also available from HLA-typed donors.

Available formats:

• Cryopreserved: Cryogenic vial containing 10.000.000 viable cells.
• Cell pellet: 1 million cells dissolved in 200µl RNAlater© for subsequent RNA, DNA or protein analysis. Cell pellets cannot be revived.

PromoKine细胞生物学(Cell Biology)是在显微、亚显微和分子水平三个层次上，研究细胞的结构、功能和各种生命规律的一门科学。细胞生物学由细胞学发展而来，细胞学是关于细胞结构与功能(特别是染色体)的研究。现代细胞生物学从显微水平、超微水平和分子水平等不同层次研究细胞的结构、功能及生命活动。在我国基础学科发展规划中，细胞生物学与分子生物学、神经生物学和生态学并列为生命科学的四大基础学科。