The anti-p53 antibody reacts with wild-type and mutant forms of human p53 antigen (Immunogen: transcription domain within the NH2-terminal region). Stains 60% of investigated carcinomas of e.g. breast, colon, pancreas.

Host	mouse
Antibody Type	monoclonal
Isotype	IgG2a
Clone	Bp53.11
Immunogen	recombinant human p53 (transcription domain within the NH2 terminus)
Purification	hybridoma cell culture supernatant
Conjugate	unconjugated
Formulation	contains 0.09% sodium azide
Storage	short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Tested species reactivity	human

Tested applications	Tested dilutions
ELISA	assay dependent
Immunocytochemistry (ICC)/ Immunofluorescence (IF)	assay dependent
Immunohistochemistry (IHC) - frozen	ready-to-use
Immunohistochemistry (IHC) - paraffin	ready-to-use (microwave treatment recommended; do not apply proteases)
Immunoprecipitation (IP)	assay dependent
Western Blot (WB)	assay dependent

PROGEN 不会在内部饲养动物以产生抗体。PROGEN 的生产仅限于使用杂交瘤细胞培养技术产生的单克隆抗体。杂交瘤克隆获得德国学术合作伙伴的许可。多克隆抗血清从工业合作伙伴处获得，例如 Seramun Diagnostica GmbH。PROGEN 只选择严格遵守动物福利指导方针的合作者。PROGEN 大力支持动物福利工作，并积极参与创新方法的开发，以在不使用动物的情况下生成优质抗体。该公司已经提供了一种高效的噬菌体展示技术，用于生产重组、定制的抗体。这种方法的优势不仅在于避免使用动物，而且还可以生成定制的、可靠的抗体。