Product Description
1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine with conjugated methoxyl poly(ethylene glycol) (DSPE-mPEG) is a聽linear聽phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome or micelle formation materials that can be used for drug delivery. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.
nanosoftpolymers/DSPE-PEG-Biotin/DSPE-PEG-BIO/2356-2000-500 mg/500 mg
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2020-07-06 16:50
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DSPE-PEG-Biotin
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[biotinyl(polyethylene glycol)] (DSPE-PEG-BIO)
Description
Additional information
Product Description
DSPE-PEG-Biotin (DSPE-PEG-BIO) is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a biotin. It is a useful self-assembling reagent to prepare grafted or PEGylated liposome or micelle while also providing an biotin group for binding to avidin or streptavidin.
It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the biotin group to non-covalently bind to targeting molecules including antibody, aptamer, protein, and peptide.
Additional information
Molecular size
1000, 2000, 3400, 5000
Package size
100 mg, 500 mg, 1g
