Product Description
Amphiphilic block copolymers comprised of poly(lactic acid-co-glycolic acid) and poly(ethylene glycol) are thermogelling materials with biodegradable blocks. The thermogel forming biodegradable delivery system has two major benefit : 1) First, thermogelation allows for delivery over the course of a period of time after introduction of what is initially a liquid; 2) The material safely biodegrades away once it is no longer necessary to lactic and glycolic acids as well as the water-soluble poly(ethylene glycol) block, which at molecular weights below 20KDa are safely eliminated from the body by the kidneys.
The thermogelation properties of poly(lactic acid-co-glycolic acid)-block-poly(ethylene glycol)-block-poly(lactic acid-co-glycolic acid) (PLGA-PEG-PLGA) copolymers have been extensively used in research for controlled delivery.

nanosoftpolymers/DSPE-PEG-Biotin/DSPE-PEG-BIO/2356-2000-500 mg/500 mg
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2020-07-06 16:50
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DSPE-PEG-Biotin
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[biotinyl(polyethylene glycol)] (DSPE-PEG-BIO)
Description
Additional information
Product Description
DSPE-PEG-Biotin (DSPE-PEG-BIO) is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a biotin. It is a useful self-assembling reagent to prepare grafted or PEGylated liposome or micelle while also providing an biotin group for binding to avidin or streptavidin.
It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the biotin group to non-covalently bind to targeting molecules including antibody, aptamer, protein, and peptide.
Additional information
Molecular size
1000, 2000, 3400, 5000
Package size
100 mg, 500 mg, 1g