Product Description
Methoxy poly(ethylene glycol)-Iodolacetyl (MPEG-IA) is one type of linear monofunctional PEG acid reagents. 聽PEG-IA can be used to react with thiol聽groups.
Haloacetyl reaction chemistry: The most commonly used haloacetyl crosslinkers contain an iodoacetyl or a bromoacetyl group. Haloacetyls react with sulfhydryl groups at physiologic pH. The reaction of the iodoacetyl group proceeds by nucleophilic substitution of iodine with a sulfur atom from a sulfhydryl group, resulting in a stable thioether linkage.
nanosoftpolymers/DSPE-PEG-Biotin/DSPE-PEG-BIO/2356-2000-500 mg/500 mg
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2020-07-06 16:50
单价：6528.00元/
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公司介绍
DSPE-PEG-Biotin
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[biotinyl(polyethylene glycol)] (DSPE-PEG-BIO)
Description
Additional information
Product Description
DSPE-PEG-Biotin (DSPE-PEG-BIO) is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a biotin. It is a useful self-assembling reagent to prepare grafted or PEGylated liposome or micelle while also providing an biotin group for binding to avidin or streptavidin.
It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the biotin group to non-covalently bind to targeting molecules including antibody, aptamer, protein, and peptide.
Additional information
Molecular size
1000, 2000, 3400, 5000
Package size
100 mg, 500 mg, 1g
